Paediatric Hematology

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Paediatric Hematology

We provide high quality services for all type of blood problems in children both non cancerous conditions like ITP, anemia etc and cancerous condition like Leukemia’s (Blood cancer), etc

Thalassemia

Thalassemia is an inherited blood disorder that causes your body to have less hemoglobin than normal. Hemoglobin enables red blood cells to carry oxygen. Thalassemia can cause anemia, leaving you fatigued.

If you have mild thalassemia, you might not need treatment. But more severe forms might require regular blood transfusions. You can take steps to cope with fatigue, such as choosing a healthy diet and exercising regularly.

Symptoms: There are several types of thalassemia. The signs and symptoms you have depend on the type and severity of your condition.

Blood Cancer

Types of blood cancer:

Acute lymphoblastic leukemia, Acute myeloid leukemia, Juvenile Myelomonocytic Leukemia (JMML), Chronic myeloid leukemia.

Most blood cancers, also called hematologic cancers, start in the bone marrow, which is where blood is produced. Blood cancers occur when abnormal blood cells start growing out of control, interrupting the function of normal blood cells, which fight off infection and produce new blood cells.

Lymphoma

Lymphoma is a cancer of the lymphatic system, which is part of the body's germ-fighting network.

The lymphatic system includes the lymph nodes (lymph glands), spleen, thymus gland and bone marrow. Lymphoma can affect all those areas as well as other organs throughout the body.

Many types of lymphoma exist. The main subtypes are: Hodgkin's lymphoma (formerly called Hodgkin's disease), Non-Hodgkin's lymphoma.

What lymphoma treatment is best for you depends on your lymphoma type and its severity. Lymphoma treatment may involve chemotherapy, immunotherapy medications, radiation therapy, a bone marrow transplant or some combination of these.

Anaemia - Low Hemoglobin

Anemia is a condition in which you lack enough healthy red blood cells to carry adequate oxygen to your body's tissues. Having anemia, also referred to as low hemoglobin, can make you feel tired and weak.

There are many forms of anemia, each with its own cause. Anemia can be temporary or long term and can range from mild to severe. In most cases, anemia has more than one cause. See your doctor if you suspect that you have anemia. It can be a warning sign of serious illness.

Treatments for anemia, which depend on the cause, range from taking supplements to having medical procedures. You might be able to prevent some types of anemia by eating a healthy, varied diet.

Thrombocytopenia- Low platelet Count

Thrombocytopenia means you have fewer than 150,000 platelets per microliter of circulating blood. Because each platelet lives only about 10 days, your body normally renews your platelet supply continually by producing new platelets in your bone marrow.

Thrombocytopenia rarely is inherited; or it can be caused by a number of medications or conditions. Whatever the cause, circulating platelets are reduced by one or more of the following processes: trapping of platelets in the spleen, decreased platelet production or increased destruction of platelets.

Trapped platelets: The spleen is a small organ about the size of your fist situated just below your rib cage on the left side of your abdomen. Normally, your spleen works to fight infection and filter unwanted material from your blood. An enlarged spleen which can be caused by a number of disorders can harbor too many platelets, which decreases the number of platelets in circulation.

Bleeding and Clotting Problems-Hemophilia

Hemophilia is a rare disorder in which the blood doesn't clot in the typical way because it doesn't have enough blood-clotting proteins (clotting factors). If you have hemophilia, you might bleed for a longer time after an injury than you would if your blood clotted properly.

Small cuts usually aren't much of a problem. If you have a severe form of the condition, the main concern is bleeding inside your body, especially in your knees, ankles and elbows. Internal bleeding can damage your organs and tissues and be life-threatening.

Hemophilia is almost always a genetic disorder. Treatment includes regular replacement of the specific clotting factor that is reduced. Newer therapies that don't contain clotting factors also are being used.

Aplastic Anaemia

Aplastic anemia is a condition that occurs when your body stops producing enough new blood cells. The condition leaves you fatigued and more prone to infections and uncontrolled bleeding.

A rare and serious condition, aplastic anemia can develop at any age. It can occur suddenly, or it can come on slowly and worsen over time. It can be mild or severe.

Treatment for aplastic anemia might include medications, blood transfusions or a stem cell transplant, also known as a bone marrow transplant.

Immunity Defects-Low White Blood Cell Counts.

A lowered level of immunity is called immunosuppression. Certain diseases, including cancer, and certain treatments, including chemotherapy and radiation therapy, can cause some people to have immunosuppression. This is usually referred to as having a low white blood cell count, but you might hear other words to describe it too.

You might hear your doctor or nurse talk about your absolute neutrophil count or ANC. This is the number of neutrophils you have in a certain amount of blood. Your health care team will use your ANC to get an idea of how well your immune system might work during treatment. A blood test called a complete blood count (CBC) is used to see how well your immune system is working. It measures your white blood cells (WBCs), and your cancer care team is able to figure out your ANC from your WBC count. Your cancer care team will use your ANC to get an idea of how your immune system is affected by treatment and how well it is working to protect you from infection.

Sickle Cell Disease (SCD)

Sickle cell anemia is one of a group of inherited disorders known as sickle cell disease. It affects the shape of red blood cells, which carry oxygen to all parts of the body.

Red blood cells are usually round and flexible, so they move easily through blood vessels. In sickle cell anemia, some red blood cells are shaped like sickles or crescent moons. These sickle cells also become rigid and sticky, which can slow or block blood flow.

There's no cure for most people with sickle cell anemia. Treatments can relieve pain and help prevent complications associated with the disease.

Myelodysplastic Syndrome (MDS)

Myelodysplastic syndrome (MDS) is a group of bone marrow disorders characterized by abnormal production of blood cells. It often leads to low blood cell counts (anemia, thrombocytopenia, or neutropenia) causing fatigue, easy bruising, and increased susceptibility to infections. MDS can progress to acute myeloid leukemia in some cases. Treatment options include supportive care, blood transfusions, growth factors, and bone marrow transplantation, depending on the severity and subtype of MDS.

Thrombosis

Thrombosis is a serious condition where one or more clots form inside of your blood vessels. When this happens, the clot can block blood flow where it formed, or it can break loose and move to somewhere else in your body. If a moving clot gets stuck in a critical area, this can cause deadly conditions like stroke and heart attack.

Thrombosis is a serious condition where a clot forms inside a blood vessel (an artery or vein) in your body or sometimes inside of your heart. This is dangerous because clots that form inside blood vessels can block blood flow. They can also break free and travel elsewhere in your body, and if a clot gets stuck in a critical location like your lungs or brain, that can cause life-threatening emergencies.

Who does it affect? Thrombosis can happen to people at any age, but it’s more common as people get older. This condition is also much more likely to happen when you have certain medical conditions. Some of those conditions include: Atrial fibrillation, Cancer, Diabetes, Heart disease.

Fanconi Anaemia

Fanconi anemia is a rare disease passed down through families (inherited) that mainly affects the bone marrow. It results in decreased production of all types of blood cells.

This is the most common inherited form of aplastic anemia. Fanconi anemia is different from Fanconi syndrome, a rare kidney disorder.

Causes

Fanconi anemia is due to an abnormal gene that damages cells, which keeps them from repairing damaged DNA.

To inherit Fanconi anemia, a person must get one copy of the abnormal gene from each parent.

The condition is most often diagnosed in children between 3 and 14 years old.